Dementia: Dementia is a disorder that can cause changes in the frontal and temporal lobes of the brain, which can cause flat affect in dementia patients. Autism: Autistic people may also struggle with flat affect and respond to social interactions.Antidepressants: Certain medications can cause flat affect as evidenced in a 2017 study where more than 3000 participants were reviewed.While flat affect is commonly linked with schizophrenia, there might be other causes of flat affect as well. While there may be a lack of evidence to prove what exactly causes flat affect, researchers believe that your brain’s chemical imbalance may be a contributing factor. Indifferent body language, gestures, or body cues.Some common signs of flat affect can include: I mean, imagine what your loved ones would feel if they threw you a surprise party and instead of meeting with a pleasantly shocked and excited reaction, they’re met with a bored or indifferent one?
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